Bon Voyage has SecuRom on it, which is a controversial anti-piracy program. There have been many cases of it preventing either the game from running at all, or going as far as to disable transfer ports/devices/programs on the computer (i.e. USB ports, CD drives, burning software, etc.) It's a possibility that's what's going on with your computer.
I'm sure that you can find some more info on MATY about it
(mainly in this post), and also by doing a search for "SecuRom". They do have a method on how to get rid of it, but the only drawback is that you won't be able to play the BV expansion, or any other game that has SecuRom included with it... :angel: